Thirteen players were listed on the Philadelphia Eagles injury report on Wednesday.
Six of them, all starters, did not participate.
The Lions meanwhile didn't have a player sit out of their preparation day, even tackle Taylor Decker was back to work with his back injury.
The NFL often times is a battle of attrition, but the Lions say that no matter lined up against them on Sunday, they need to be ready for their best.
"Maybe just a little bit more for me to look at, but it's a challenge anytime you play in this league," Lions quarterback Matthew Stafford said.
The Lions will practice again Thursday and Friday before leaving for Philadelphia on Saturday.