4:13 PM, Feb 27, 2020


Cleveland Clinic researchers say 'broken heart syndrome' on the rise amid pandemic

Posted at 3:21 PM, Jul 10, 2020

During the COVID-19 pandemic, researchers at the Cleveland Clinic have found a significant increase in patients experiencing stress cardiomyopathy, also known as "broken heart syndrome," which has symptoms similar to a heart attack, according to a new study from the clinic.

“Especially when it comes to the loss of a job and economic stressors, those are things that the COVID pandemic is affecting in many people,” said Dr. Grant Reed. “So it’s not just the virus itself that’s causing illness in patients.”

Heartbreak is a common thread in movies, pop culture, and music but Cleveland Clinic cardiologists are warning patients about the serious effects of a broken heart and the possible connection with the COVID-19 pandemic.

“No one really expected to be in this situation and the pandemic has put dramatic, unprecedented stressors on our life,” Reed said. “These are patients that are coming in presenting very similar to how patients come in with a heart attack. They have EKG changes consistent with a heart attack and they have chest discomfort.”

Researchers said stress cardiomyopathy happens in response to physical or emotional stress, which causes dysfunction or failure in the heart muscle.

“The COVID-19 pandemic has brought about multiple levels of stress in people’s lives across the country and world. People are not only worried about themselves or their families becoming ill, but they are also dealing with economic and emotional issues, societal problems and potential loneliness and isolation,” said Ankur Kalra, M.D., a Cleveland Clinic cardiologist in the Sections of Invasive and Interventional Cardiology and Regional Cardiovascular Medicine, who led the study.

Patients with this condition have experienced symptoms similar to a heart attack, such as chest pain, shortness of breath, but usually don’t have acutely blocked coronary arteries.

“The stress can have physical effects on our bodies and our hearts, as evidenced by the increasing diagnoses of stress cardiomyopathy we are experiencing,” said Kalra.

Patients can also experience irregular heartbeat, fainting, low blood pressure, and cardiogenic shock, which happens when the heart can’t pump enough blood to meet the body’s demand due to stress hormones.

Researchers have admitted the causes of stress cardiomyopathy are not fully understood.

Between March 1 and April 30, cardiologists looked at 258 patients with heart symptoms coming into Cleveland Clinic and Cleveland Clinic Akron General. Researchers compared them with four control groups and found a “significant increase” in patients diagnosed with cardiomyopathy, reaching 7.8% compared with a pre-pandemic incidence of 1.7%, the release states.

All patients diagnosed with stress cardiomyopathy tested negative for COVID-19. Those with the condition since the COVID-19 outbreak had a longer hospital stay compared to those pre-pandemic. Doctors said patients with stress cardiomyopathy patients generally recover in a matter of days or weeks, although the condition can occasionally cause major adverse cardiac and cerebrovascular events.

“For those who feel overwhelmed by stress, it’s important to reach out to your healthcare provider. Exercise, meditation, and connecting with family and friends, while maintaining physical distance and safety measures, can also help relieve anxiety," said Grant Reed, director of Cleveland Clinic’s STEMI program and senior author for the study.

Reed said a number of factors can cause heart function to deteriorate, which include loneliness, financial stress, or overwhelming feelings of uncertainty brought on by stay-at-home orders.

“You have to recognize when you need to seek help and say, ‘Okay I need to take a step back.’ Maybe disconnect from social media and not read so much because that can stress us all out,” Reed said.

Researchers noted that additional research is needed in this area, especially if this trend in cases is present in other regions of the country.

WEWS' Kaylyn Hlavaty and Emily Hamilton first reported this story.