Genetics: More Than Merely a Mutated Gene
If two women have the same genetic mutation that puts them at higher-than-average risk for a disease such as breast cancer, why does only one develop the disease? In the current issue of PLoS Genetics, Michigan State University genetic scientists have begun to understand how the rest of the genome interacts with such mutations to cause the differences we see among individuals. It’s likely that most diseases with a suspected genetic component, such as cancer, asthma or Parkinson’s, involve reactions between more than one set of genes. For Dworkin and Chari, the next step is to tease apart the intricacies of what’s happening.
The research is funded by the National Science Foundation grant number MCB 0922344.
SOURCE: PRESS RELEASE, MSUTODAY